Two sample MR report
FUOM_Monocyte (Mono) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.8631339 | 0.7293942 | 0.3218980 |
| Weighted median | 5 | -0.0633213 | 0.0515010 | 0.2188788 |
| Inverse variance weighted | 5 | -0.0896820 | 0.0391886 | 0.0221100 |
| Simple mode | 5 | -0.0466360 | 0.0740716 | 0.5631230 |
| Weighted mode | 5 | -0.0458878 | 0.0716614 | 0.5567907 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.3970486 | 3 | 0.9408515 |
| Inverse variance weighted | 2.1084379 | 4 | 0.7158224 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.5819386 | 0.4448389 | 0.2820121 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 3.84e-05 | 0 | TRUE | 0.5577439 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
